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The composition in the unliganded double mutant HIV-1 RT confirmed that Lys103Asn mutation facilitates coordination of the sodium ion with Lys101 O, Asn103 N and O(delta1), Tyr188 O(eta), and two h2o molecules. The formation in the binding pocket requires the removal on the sodium ion. Even though the RT on your own as well as RT/HBY 097 intricate